Spectrophotometric and Atomic Absorption Determination of Ramipril, Enalapril Maleate and Fosinopril through Ternary Complex Formation with Molybdenum (V)-Thiocyanate (Mo(V)-SCN)

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Spectrophotometric and atomic absorption determination of ramipril, enalapril maleate and fosinopril through ternary complex formation with molybdenum (V)-thiocyanate (Mo(V)-SCN).

Three different sensitive and accurate spectroscopic procedures were developed for the determination of three angiotensin-converting enzyme inhibitors, namely, ramipril, enalapril maleate and fosinopril. The first two spectrophotometric (extractive and non-extractive) procedures were based on ternary complex formation with molybdenum(V) thiocyanate. The formed complex can be determined by extra...

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Extractive Spectrophotometric Determination of some Drugs Through Ion-Pair Complex Formation with Thiocyanate wnd Cobalt (II) or Molybdenum (V)

Two rapid, simple and sensitive extractive specrophotometric methods has been developed for the assay of Hyoscine butyle bromide (HBB), losartan potassium (LSR) and Sertaline HCl (SER) in bulk and in their pharmaceutical formulations. The proposed methods depend upon the reaction of cobalt(II)–thiocyanate (method A) and molybdenum(V)–thiocyanate ions (method B) with the cited drugs to form stab...

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Optimized and Validated Spectrophotometric Methods for the Determination of Enalapril Maleate in Commercial Dosage Forms

Four simple, rapid and sensitive spectrophotometric methods have been proposed for the determination of enalapril maleate in pharmaceutical formulations. The first method is based on the reaction of carboxylic acid group of enalapril maleate with a mixture of potassium iodate (KIO(3)) and iodide (KI) to form yellow colored product in aqueous medium at 25 +/- 1 degrees C. The reaction is followe...

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ژورنال

عنوان ژورنال: Chemical and Pharmaceutical Bulletin

سال: 2008

ISSN: 0009-2363,1347-5223

DOI: 10.1248/cpb.56.1521